Bibliography

Pakola SJ and Grunwald JE: Effects of oxygen and carbon dioxide on human retinal circulation. Investigative Ophthalmology & Visual Science 34(10): 2866-70, 1993.

MacGregor RR, Pakola SJ, Graziani AL, et al: CMV infection in clinically stable HIV-infected individuals with CD4-positive lymphocyte counts below 100/ul of blood: prevalence and relationship to risk of subsequent CMV retinitis. Journal of AIDS 10:324-30, 1995.

Pakola SJ, Dinges DF, Pack AI: Review of regulations and guidelines for commercial and noncommercial drivers with sleep apnea and narcolepsy. Sleep 18 (9): 787-96, 1995.

Pakola SJ, Nichols CW: CD8+ cells and cytomegalovirus retinitis in AIDS patients (correspondence). Am. J. Ophthalmol. 121(4): 455, 1996.

Bennett J, Pakola S, Zenk Y, Maguire A: Humoral response after administration of E1-deleted adenoviruses: immune privilege of the subretinal space. Human Gene Therapy 7(14): 1763-9, 1996.

Balcer L, Galetta S, Bagley L, Pakola S: Localization of traumatic oculomotor nerve palsy to the midbrain exit sight by M.R.I. Am. J. Ophthalmol. 122(3): 437-9, 1996.

Lapchak PA, Araujo DM, Pakola SJ, Song D, Wei J, Zivin JA.: Microplasmin: a novel thrombolytic that improves behavioral outcome after embolic strokes in rabbits. Stroke. 33: 2279-2284, 2002.

Armstrong PW, Burton J, Pakola S, Molhoek PG, Betriu A, Tendera M, Bode C, Adgey AA, Bar F, Vahanian A, Van de Werf F; CAPTORS II Investigators. Collaborative Angiographic Patency Trial Of Recombinant Staphylokinase (CAPTORS II). Am Heart J. 146(3):484-8, 2003.

Sakuma T, Tanaka M, Mizota A, Junji Inoue J, Pakola S. Safety of in vivo pharmacologic vitreolysis with recombinant microplasmin in rabbit eyes. Invest Ophthal Vis Sci. 2005 Sep;46(9):3295-9.

Rasmussen RS, Overgaard K, Pakola S, Boysen G. Microplasmin may improve recovery in a rat embolic stroke model. Neurol Res. 30(1): 75-81, 2008.

de Smet MD, Gandorfer A, Stalmans P, Veckeneer M, Feron E, Pakola S, Kampik A. Microplasmin intravitreal administration in patients with vitreomacular traction scheduled for vitrectomy: the MIVI I trial. Ophthalmology. 2009 Jul;116(7):1349-55, 1355.e1-2. Epub 2009 May 17.

Pakola S, Cahillane G, Stassen JM, Lijnen HR, Verhamme P . Neutralization of alpha(2)antiplasmin by microplasmin: a randomized, double-blind, placebo-controlled, ascending-dose study in healthy male volunteers. Clin Ther. 2009 Aug;31(8):1688-706.

Benz MS, Packo KH, Gonzalez V, Pakola S, Bezner D, Haller JA, Schwartz SD. A placebo-controlled trial of microplasmin intravitreous injection to facilitate posterior vitreous detachment before vitrectomy. Ophthalmology. 2010 Apr;117(4):791-7.

Verhamme P, Pakola S, Jensen TJ, Berggren K, Sonesson E, Saint-Remy JM, Balchen T, Belmans A, Cahillane G, Stassen JM, Peerlinck K, Glazer S, Jacquemin M. Tolerability and pharmacokinetics of TB-402 in healthy male volunteers. Clin Ther. 2010 Jun;32(6):1205-20.

Stalmans P, Delaey C, de Smet MD, van Dijkman E, Pakola S. Intravitreal injection of microplasmin for treatment of vitreomacular adhesion: results of a prospective, randomized, sham-controlled phase II trial (the MIVI-IIT trial). Retina. 2010 Jul-Aug;30(7):1122-7.

Martinsson-Niskanen T, Riisbro R, Larsson L, Winstedt L, Stenberg Y, Pakola S, Stassen JM, Glazer S. Monoclonal Antibody TB-403: A First-in-Human, Phase I, Double-Blind, Dose Escalation Study Directed Against Placental Growth Factor in Healthy Male Subjects. Clin Ther. 2011 Sep;33(9):1142-9. Epub 2011 Sep 8.

Lassen U, Nielsen DL, Sørensen M, Winstedt L, Niskanen T, Stenberg Y, Pakola S, Stassen JM, Glazer S. A phase I, dose-escalation study of TB-403, a monoclonal antibody directed against PlGF, in patients with advanced solid tumours. Br J Cancer. 2012 Feb 14;106(4):678-84. doi: 10.1038/bjc.2011.609. Epub 2012 Jan 24.

Verhamme P, Heye S, Peerlinck K, Cahillane G, Tangelder M, Fourneau I, Daenens K, Belmans A, Pakola S, Verhaeghe R, Maleux G. Catheter-directed thrombolysis with microplasmin for acute peripheral arterial occlusion (PAO): an exploratory study. Int Angiol. 2012 Jun;31(3):289-96.

Stalmans P., Benz MS., Gandorfer, Kampik, A, Girach A, Pakola S, Haller JA for the MIVI-TRUST Study Group. Enzymatic Vitreolysis with Ocriplasmin for Vitreomacular Traction and Macular Holes. N Engl J Med 2012; August 16; 367:606-615.

Folgar FA, Toth CA, Decroos FC, Girach A, Pakola S, Jaffe GJ. Assessment of retinal morphology with spectral and time domain OCT in the phase III trials of enzymatic vitreolysis. Invest Ophthalmol Vis Sci. 2012 Oct 2. [Epub ahead of print]

Decroos FC, Toth CA, Folgar FA, Pakola S, Stinnett SS, Heydary CS, Burns R, Jaffe GJ. Characterization of Vitreoretinal Interface Disorders Using OCT in the Interventional Phase 3 Trials of Ocriplasmin. Invest Ophthalmol Vis Sci. 2012 Sep 21;53(10):6504-11. Print 2012.

Haller JA, Stalmans P, Benz MS, Gandorfer A, Pakola SJ, Girach A, Kampik A, Jaffe GJ, Toth CA on behalf of the MIVI-TRUST Study Group. Efficacy of Intravitreal Ocriplasmin for Treatment of Vitreomacular Adhesion: Subgroup Analyses From Two Randomized Trials. Ophthalmology. 2015 Jan; 122(1):117-22. Epub 2014 Sep 18.

Gandorfer A, Benz MS, Haller JA, Stalmans P, Pakola SJ, Girach A, Kampik A, Toth CA, Jaffe GJ; for the MIVI-TRUST Study Group. Association between anatomical resolution and functional outcomes in the MIVI-TRUST studies using ocriplasmin to treat symptomatic vitreomacular adhesion/vitreomacular traction, including when associated with macular hole. Retina. 2015 Jun;35(6):1151-7.

Li G, Nottebaum AF, Brigell M, Navarro ID, Ipe U, Mishra S, Gomez-Caraballo M, Schmitt H, Soldo B, Pakola S, Withers B, Peters KG, Vestweber D, Stamer WD. A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure. Invest Ophthalmol Vis Sci. 2020 Dec 1;61(14):12

Campochiaro PA, Avery R, Brown D, Heier J, Ho AC, Huddleston S, Jaffe G, Khanani A, Pakola S, Pieramici D, Wykoff C, Van Everen S. A Phase I/IIa Dose-escalation Study of Gene Therapy by Subretinal Delivery of RGX-314 for Neovascular AMD. The Lancet. 2024 Apr 20;403(10436):1563-1573. doi: 10.1016/S0140-6736(24)00310-6. Epub 2024 Mar 27.

Pack AI, Pakola SJ, Findley LJ: Regulations for driving for patients with sleep disorders. In Forensic aspects of sleep (Edited by Shapiro C, McCall-Smith). A. John Wiley & Sons Limited, 1996.

Girach A & Pakola S. Vitreomacular interface diseases: pathophysiology, diagnosis and future treatment. Exp. Rev. Ophthalmology. 7(4), 2012.

Haller J & Pakola S: Pharmacologic Vitreolysis – Clinical Trial Data. In Diseases of the Vitreo-macular Interface (Edited by Girach A & De Smet M). Springer, 2012.